Detalhe da pesquisa
1.
Chloropyridinyl Esters of Nonsteroidal Anti-Inflammatory Agents and Related Derivatives as Potent SARS-CoV-2 3CL Protease Inhibitors.
Molecules
; 26(19)2021 Sep 24.
Artigo
Inglês
| MEDLINE | ID: mdl-34641337
2.
Computational modeling of the bat HKU4 coronavirus 3CLpro inhibitors as a tool for the development of antivirals against the emerging Middle East respiratory syndrome (MERS) coronavirus.
J Mol Recognit
; 30(11)2017 11.
Artigo
Inglês
| MEDLINE | ID: mdl-28608547
3.
Indole Chloropyridinyl Ester-Derived SARS-CoV-2 3CLpro Inhibitors: Enzyme Inhibition, Antiviral Efficacy, Structure-Activity Relationship, and X-ray Structural Studies.
J Med Chem
; 64(19): 14702-14714, 2021 10 14.
Artigo
Inglês
| MEDLINE | ID: mdl-34528437
4.
A small molecule compound with an indole moiety inhibits the main protease of SARS-CoV-2 and blocks virus replication.
Nat Commun
; 12(1): 668, 2021 01 28.
Artigo
Inglês
| MEDLINE | ID: mdl-33510133
5.
Preclinical characterization of an intravenous coronavirus 3CL protease inhibitor for the potential treatment of COVID19.
Nat Commun
; 12(1): 6055, 2021 10 18.
Artigo
Inglês
| MEDLINE | ID: mdl-34663813
6.
Discovery of a Novel Inhibitor of Coronavirus 3CL Protease for the Potential Treatment of COVID-19.
bioRxiv
; 2021 Feb 12.
Artigo
Inglês
| MEDLINE | ID: mdl-32935104
7.
X-Ray Structure and Inhibition of 3C-like Protease from Porcine Epidemic Diarrhea Virus.
Sci Rep
; 6: 25961, 2016 05 13.
Artigo
Inglês
| MEDLINE | ID: mdl-27173881